Legendary sitcom director James Burrows feels sanguine about being Conan O’Brien’s friend.

James sits down with Conan to talk about his new book Directed by James Burrows, casting for Cheers and Frasier, which of his shows he still thinks is the funniest, and the evolution of the Norm-ism. Plus, Conan tries to get to know his own feet a bit better.

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Conan chats with Kevin in Juárez, Mexico about working in a candy factory and the one bit of American history Conan thinks every first-time visitor should know.

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Actor Luke Wilson feels that, on the advice of his counsel, it’s best that he agree to be clear about being Conan O’Brien’s friend.

Luke sits down with Conan to chat about interacting with the pioneers of his craft, mastering his put-upon film persona, taking inspiration from MAD Magazine, and more. Later, Gourley mourns how the tragic power of the podcast has ruined a small part of his life.

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Conan talks with Benji from Kampala about the challenges of organizing a traditional Ugandan wedding.

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Comedian Nicole Byer feels giddy about being Conan O’Brien’s friend.

Nicole returns to chat with Conan about being loved by kids, the wisdom of John Cena, and being horny for love. Later, Conan and his team attempt to hold it together while Sona is away on her book tour.

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Conan chats with Jake in Tbilisi, Georgia about his adventures riding his motorcycle around the world.

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Actress, comedian, and producer Aubrey Plaza feels totally fine about being Conan O’Brien’s friend.

Aubrey sits down with Conan to discuss playing basketball in disguise, getting cast in her breakout role as April Ludgate on Parks and Recreation, and her new movie Emily the Criminal. Later, Sona’s assistant David Hopping tells the tale of how he came to work under Conan.

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Conan speaks with Connor from Vancouver about directing animated features and the hardships of height.

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Comedian Jeff Ross feels tan about being Conan O’Brien’s friend.

Jeff sits down with Conan to talk about learning from the great Don Rickles, his reaction to “the slap,” great moments in roast comedy history, and memories of some of the great comics lost in recent years. Later, Conan and his crew reveal the surprising and controversial way they made national news headlines.

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Conan sits down with his significant other, Liza Powel O’Brien, in this very special bonus episode from her own podcast, Significant Others. Listen as Liza and Conan chat about all things Abe and Mary Lincoln.

Conan talks to Taylor from Salt Lake City about working as a 911 operator and to walk through an emergency simulation.

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Actor, writer, and comedian B.J. Novak feels excited, but cautious about being Conan O’Brien’s friend.

B.J. sits down with Conan to talk about hailing from rival towns, the personal impact of Bob Saget, working on Punk’D, and B.J.’s new film Vengeance. Plus, Conan’s wife Liza stops by to share stories from her new podcast “Significant Others.”

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Conan talks to salon owner Kristi to get recommendations for his style and to get the scoop on the weirdest conversations she’s had with someone in the chair.

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Comedian Nikki Glaser feels chill about being Conan O’Brien’s friend.

Nikki sits down with Conan once more to discuss moving back in with her parents, handling criticism, hosting Fboy Island, and pushing the boundaries with her latest special Good Clean Filth.

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Conan talks with NASA engineer Smythe about the craziest things he’s smuggled into space and how Conan’s team would fare in the final frontier.

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